CD6 monoclonal antibody, clone MEM-98 (PE)
产品名称： CD6 monoclonal antibody, clone MEM-98 (PE)
英文名称： CD6 monoclonal antibody, clone MEM-98 (PE)
产品编号： MAB4542
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152
- 传真 : +886-2-8751-1186
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against native CD6.
- Immunogen:
- Native purified human CD6.
- Host:
- Mouse
- Theoretical MW (kDa):
- 100-130
- Reactivity:
- Human
- Specificity:
- The antibody reacts with CD6, a 100-130 kD single chain transmembrane glycoprotein expressed on T and B lymphocytes subsets, thymocytes, and acute lymphocytic leukemia cells.
- Form:
- Liquid
- Conjugation:
- PE
- Isotype:
- IgG1
- Storage Buffer:
- In PBS (0.2% BSA, 15 mM sodium azide)
- Storage Instruction:
- Store in the dark at 4°C. Do not freeze.
Avoid prolonged exposure to light.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Flow Cytometry (20 ul in human blood cells 100 ul in whole blood or 106 cells in a suspension)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Long-term engagement of CD6 and ALCAM is essential for T-cell proliferation induced by dendritic cells.
Zimmerman AW, Joosten B, Torensma R, Parnes JR, van Leeuwen FN, Figdor CG.Blood. 2006 Apr 15;107(8):3212-20. Epub 2005 Dec 13.
- 2.
- CD6 ligation modulates the Bcl-2/Bax ratio and protects chronic lymphocytic leukemia B cells from apoptosis induced by anti-IgM.
Osorio LM, De Santiago A, Aguilar-Santelises M, Mellstedt H, Jondal M.Blood. 1997 Apr 15;89(8):2833-41.
- Application Image
- Flow Cytometry
- Entrez GeneID:
- 923
- Gene Name:
- CD6
- Gene Alias:
- FLJ44171,TP120
- Gene Description:
- CD6 molecule
- Omim ID:
- 186720
- Gene Ontology:
- Hyperlink
- Gene Summary:
- CD6 is a monomeric 105- or 130-kD membrane glycoprotein that is involved in T-cell activation. The size difference between the 2 CD6 forms is due to differences in phosphorylation (Robinson et al., 1995 [PubMed 7589069]).[supplied by OMIM
- Other Designations:
- CD6 antigen
- Gene Pathway
- Related Disease