ETV6 monoclonal antibody (M01), clone 3B10
产品名称： ETV6 monoclonal antibody (M01), clone 3B10
英文名称： ETV6 monoclonal antibody (M01), clone 3B10
产品编号： H00002120-M01
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152
- 传真 : +886-2-8751-1186
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a full length recombinant ETV6.
- Immunogen:
- ETV6 (AAH43399, 1 a.a. ~ 452 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- MSETPAQCSIKQERISYTPPESPVPSYASSTPLHVPVPRALRMEEDSIRLPAHLRLQPIYWSRDDVAQWLKWAENEFSLRPIDSNTFEMNGKALLLLTKEDFRYRSPHSGDVLYELLQHILKQRKPRILFSPFFHPGNSIHTQPEVILHQNHEEDNCVQRTPRPSVDNVHHNPPTIELLHRSRSPITTNHRPSPDPEQRPLRSPLDNMIRRLSPAERAQGPRPHQENNHQESYPLSVSPMENNHCPASSESHPKPSSPRQESTRVIQLMPSPIMHPLILNPRHSVDFKQSRLSEDGLHREGKPINLSHREDLAYMNHIMVSVSPPEEHAMPIGRIADCRLLWDYVYQLLSDSRYENFIRWEDKESKIFRIVDPNGLARLWGNHKNRTNMTYEKMSRALRHYYKLNIIRKEPGQRLLFRFMKTPDEIMSGRTDRLEHLESQELDEQIYQEDEC
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG1 Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (75.46 KDa) .
- MSDS:
Download
- Publication Reference
- 1.
- ETV6 mutations in early immature human T cell leukemias.
Van Vlierberghe P, Ambesi-Impiombato A, Perez-Garcia A, Haydu JE, Rigo I, Hadler M, Tosello V, Della Gatta G, Paietta E, Racevskis J, Wiernik PH, Luger SM, Rowe JM, Rue M, Ferrando AA.J Exp Med. 2011 Dec 19;208(13):2571-9. Epub 2011 Dec 12.
- 2.
- The ETS Family Member TEL Binds to Nuclear Receptors RAR and RXR and Represses Gene Activation.
Meester-Smoor MA, Janssen MJ, Ter Haar WM, van Wely KH, Aarnoudse AJ, van Oord G, van Tilburg GB, Zwarthoff EC.PLoS One. 2011;6(9):e23620. Epub 2011 Sep 16.
- Applications
- Western Blot (Cell lysate)
- ETV6 monoclonal antibody (M01), clone 3B10 Western Blot analysis of ETV6 expression in Jurkat ( Cat # L017V1 ).
- Protocol Download
- Western Blot (Recombinant protein)
- Protocol Download
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
enlarge this image- Immunoperoxidase of monoclonal antibody to ETV6 on formalin-fixed paraffin-embedded human placenta. [antibody concentration 3 ug/ml]
- Protocol Download
- Sandwich ELISA (Recombinant protein)
- Detection limit for recombinant GST tagged ETV6 is approximately 0.1ng/ml as a capture antibody.
- Protocol Download
- Entrez GeneID:
- 2120
- GeneBank Accession#:
- BC043399
- Protein Accession#:
- AAH43399
- Gene Name:
- ETV6
- Gene Alias:
- TEL,TEL/ABL
- Gene Description:
- ets variant 6
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes an ETS family transcription factor. The product of this gene contains two functional domains: a N-terminal pointed (PNT) domain that is involved in protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma. [provided by RefSeq
- Other Designations:
- TEL oncogene,TEL1 oncogene,ets variant gene 6 (TEL oncogene)
- Gene Pathway