PDX1 purified MaxPab rabbit polyclonal antibody (D01P)
产品名称： PDX1 purified MaxPab rabbit polyclonal antibody (D01P)
英文名称： PDX1 purified MaxPab rabbit polyclonal antibody (D01P)
产品编号： H00003651-D01P
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152
- 传真 : +886-2-8751-1186
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against a full-length human PDX1 protein.
- Immunogen:
- PDX1 (AAI11593.1, 1 a.a. ~ 283 a.a) full-length human protein.
- Sequence:
- MNGEEQYYAATQLYKDPCAFQRGPAPEFSASPPACLYMGRQPPPPPPHPFPGALGALEQGSPPDISPYEVPPLADDPAVAHLHHHLPAQLALPHPPAGPFPEGAEPGVLEEPNRVQLPFPWMKSTKAHAWKGQWAGGAYAAEPEENKRTRTAYTRAQLLELEKEFLFNKYISRPRRVELAVMLNLTERHIKIWFQNRRMKWKKEEDKKRGGGTAVGGGGVAEPEQDCAVTSGEELLALPPPPPPGGAVPPAAPVAAREGRLPPGLSASPQPSSVAPRRPQEPR
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody reactive against mammalian transfected lysate.
- MSDS:
Download
- Applications
- Western Blot (Tissue lysate)
- PDX1 MaxPab rabbit polyclonal antibody. Western Blot analysis of PDX1 expression in human liver.
- Protocol Download
- Western Blot (Tissue lysate)
- PDX1 MaxPab rabbit polyclonal antibody. Western Blot analysis of PDX1 expression in mouse liver.
- Protocol Download
- Western Blot (Transfected lysate)
- Western Blot analysis of PDX1 expression in transfected 293T cell line (H00003651-T01) by PDX1 MaxPab polyclonal antibody.
Lane 1: PDX1 transfected lysate(31.13 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Entrez GeneID:
- 3651
- GeneBank Accession#:
- BC111592
- Protein Accession#:
- AAI11593.1
- Gene Name:
- PDX1
- Gene Alias:
- GSF,IDX-1,IPF1,IUF1,MODY4,PDX-1,STF-1
- Gene Description:
- pancreatic and duodenal homeobox 1
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4). [provided by RefSeq
- Other Designations:
- OTTHUMP00000018174,glucose-sensitive factor,insulin promoter factor 1, homeodomain transcription factor,insulin upstream factor 1,pancreatic-duodenal homeobox factor 1,somatostatin transcription factor 1
- Related Disease
- Atherosclerosis
- Cardiovascular Diseases
- Cerebral Infarction
- Diabetes Mellitus
- Diabetes Mellitus, Type 1
- Diabetes Mellitus, Type 2
- Diabetes, Gestational
- Edema
- Genetic Predisposition to Disease
- Glucose Intolerance
- Hypercholesterolemia
- Hypertension
- Intracranial Arteriosclerosis
- Kidney Failure, Chronic
- Metabolic Syndrome X
- Myocardial Infarction
- Obesity
- Renal Insufficiency, Chronic
- Werner syndrome