RAF1 (Human) Recombinant Protein-蛋白质/抗原/多肽-试剂-生物在线
RAF1 (Human) Recombinant Protein

RAF1 (Human) Recombinant Protein

商家询价

产品名称： RAF1 (Human) Recombinant Protein

英文名称： RAF1 (Human) Recombinant Protein

产品编号： P4210

产品价格： 0

产品产地： 台湾

品牌商标： Abnova

更新时间： null

使用范围： null

亚诺法生技股份有限公司（Abnova)
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  • Specification
  • Product Description:
  • Human RAF1 (P04049) full-length recombinant protein expressed in Sf9 cells.
  • Theoretical MW (kDa):
  • 63
  • Form:
  • Liquid
  • Preparation Method:
  • Insect cell (Sf9) expression system
  • Purity:
  • ≥ 85% by SDS-PAGE
  • Activity:
  • The specific activity of RAF1(EE) was determined to be ~6,000 nmol/min/mg in a coupled assay as per activity assay protocol.
  • Storage Buffer:
  • In 50 mM Tris-HCl, 150 mM NaCl, pH 7.5 (0.25 mM Dithiothreitol, 0.1 mM EGTA, 0.1 mM EDTA, 25% glycerol, 0.1 mM PMSF)
  • Storage Instruction:
  • Store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Quality Control Testing:
  • SDS-PAGE Result

    QC Testing of P4210
  • Note:
  • Result of activity analysis

  • Applications
  • Functional Study
  • SDS-PAGE
  • Application Image
  • Functional Study
  • SDS-PAGE
  • Gene Information
  • Entrez GeneID:
  • 5894
  • Gene Name:
  • RAF1
  • Gene Alias:
  • CRAF,NS5,Raf-1,c-Raf
  • Gene Description:
  • v-raf-1 murine leukemia viral oncogene homolog 1
  • Gene Summary:
  • This gene is the cellular homolog of viral raf gene (v-raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine/threonine specific protein kinases, ERK1 and ERK2. Activated ERKs are pleiotropic effectors of cell physiology and play an important role in the control of gene expression involved in the cell division cycle, apoptosis, cell differentiation and cell migration. Mutations in this gene are associated with Noonan syndrome 5 and LEOPARD syndrome 2. [provided by RefSeq
  • Other Designations:
  • Oncogene RAF1,raf proto-oncogene serine/threonine protein kinase
  • Interactome

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